Effect of Irbesartan on the level of serum high-sensitivity C-reactive protein in patients with acute cerebral infarction
- VernacularTitle:厄贝沙坦对急性脑梗死患者血清超敏C反应蛋白水平的影响
- Author:
Jingping SHI
;
Jingde DONG
;
Wenzhuo DAI
- Publication Type:Journal Article
- Keywords:
Irbesartan;
high-sensitivity C-reactive protein;
cerebral infarction
- From:
Journal of Clinical Neurology
1988;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Irbesartan on the level of serum high-sensitivity C-reactive protein(hs-CRP) in the patients with acute cerebral infarction(ACI).Methods 60 patients with ACI were randomly assigned to Irbesartan therapy group(n=30) treated with Irbesartan 150 mg/d combined Aspirin 100 mg/d and conventional therapy group(n=30) treated with Aspirin 100 mg/d.Both groups were treated for 14 consecutive days and the other measures of symptomatic therapy were same.And another 30 patients without cerebrovascular diseases were selected as control group.The levels of serum hs-CRP were measured and the scores of neurological deficit(NDS) were evaluated before and after treatment.Results(1) Before treatment the levels of serum hs-CRP of ACI patients in both therapy groups were significantly higher than that in control group(all P
