Biocompatibility of three kinds of endovascular stents
- VernacularTitle:三种不同材料血管内支架的生物相容性
- Author:
Shuang SU
;
Wanfu LI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
Nondegradable stent graft and drug-eluting stent inhibit intima hyperplasy to certain extent, reduce the incidence of restenosis, and probabilize the treatment of coronary artery disease. However, the stent is a metallic foreign body, so it can induce thrombogenesis or immune responses. Novel biodegradable stent has good biocompatibility and biodegradation. It can degrade into CO2 and H2O2, participate metabolism, with no toxicity or complication caused by permanent metal stent. However, the biodegradable stent possesses inadequate mechanical performance and support. How to improve the biological stability and controllability through optimizing material integral quality and modulating their molecular constitution, and how to reduce inflammatory reaction and vascular restenosis after stenting are the study focuses in medical and material fields.
