The relationship between the serum ghrelin level and ?-cell function after treatment of patients with newly diagnosed type 2 diabetes mellitus
- VernacularTitle:初诊2型糖尿病治疗后血清ghrelin水平与胰岛?细胞功能的关系
- Author:
Ying HU
;
Qiao ZHANG
;
Lixin SHI
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus,newly diagnosed;
Ghrelin;
Pancreatic ?-cell function
- From:
Chinese Journal of Diabetes
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the serum ghrelin level and ?-cell function after treatment of patients with newly diagnosed type 2 diabetes mellitus.Methods 34 patients with newly diagnosed type 2 diabetes mellitus were divided into three groups of pre-treatment(DM0),two weeks after treatment(DM1)and six months after treatment(DM2).Intravenous glucose tolerance tests(IVGTT)were performed and blood glucose,HbA1C,ghrelin,insulin were measured during the study.Insulin sensitivity was assessed by homeostasis model assessment(HOMA).Results(1)Compared with DM0 group,beta-cell function and the mean AUC of insulin were dramatically improved in groups of DM1 and DM2(all P
