Effects of diabetes mellitus on apoptotic cytokines and inflammatory cytokines in patients with acute myocardial infarction
- VernacularTitle:糖尿病对急性心肌梗死患者细胞凋亡因子和炎性因子的影响
- Author:
Guojie CHENG
;
Liang CUI
;
Haixia WU
- Publication Type:Journal Article
- Keywords:
Myocardial infarction,acute;
Diabetes mellitus;
Cardiomyocyte apoptosis;
Inflammatory response
- From:
Chinese Journal of Diabetes
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of diabetes mellitus(DM)on fas receptor-induced cardiomyocytes apoptosis and inflammatory response in patients with acute myocardial infarction(AMI).Methods 70 patients with ST-elevated myocardial infarction were divided into two groups:without(n=36)and with diabetes mellitus(n=34).Strepavidin-biotin ELISA was used to examine the serum levels of sFas,sFasL,TNF-? and IL-6.Results As the concentrations of sFas and sFasL immediately after primary PCI were higher in patients of AMI with DM than without DM(4.18?0.86 vs 3.30?0.82 ng/ml,6.15?1.56 vs 4.34?1.37 ng/ml,respectively,P
