Transurethral Electroresection Combined with Intravesical Irrigation with Epirubicin for Cystitis Glandularis:Report of 130 Cases
- VernacularTitle:经尿道电切术联合术后表柔比星膀胱灌注治疗腺性膀胱炎(附130例报告)
- Author:
Haitao FAN
;
Yi ZHOU
;
Wencui XU
- Publication Type:Journal Article
- Keywords:
Cystitis glandularis;
Transurethral electroresection
- From:Chinese Journal of Minimally Invasive Surgery
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of transurethral electroresection combined with intravesical irrigation with epirubicin for cystitis glandularis.Methods From January 2000 to January 2006,130 patients with cystitis glandularis were treated with transurethral electroresection.The whole depth of diseased mucosa and adjacent normal mucosal tissues(1 cm away)were resected.One week after the operation,intravesical irrigation with epirubicin were carried out(50 mg per time,once a week for 8 weeks,and then once a month for 2 years).Results Five of the patients developed urethral stenosis after the electroresection,and were cured by dilating the urethra at a regular interval.No complications occurred in the other patients.Bladder symptoms disappeared in 98 patients;23 cases had urinary symptoms occasionally,but cystoscopy showed normal vesical mucosa.Nine of the patients had recurrent cystitis,5 of which showed non-irrigation-induced hematuria 6-12 months after the operation,and 4 were found during regular re-examination by cystoscopy.Transurethral electroresection was performed again on these 9 patients,after they were diagnosed by biopsy;and then intravesical irrigation with hydroxycamptothecin(20 mg per time)were given.They were followed up for 12 months,during which no one had recurrence.Conclusions Transurethral electroresection combined with intravesical chemotherapy is effective for cystitis glandularis.The method is worth being widely used.
