Progress in researches of melanoma inhibitory activity in cartilage destruction
- VernacularTitle:黑色素瘤抑制蛋白在软骨损伤中的研究进展
- Author:
Jihe BAN
;
Jianning ZHAO
- Publication Type:Journal Article
- Keywords:
Melanoma inhibitory activity;
Cartilage derived retinoic acid-sensitive protein;
Cartilage;
Biomarker
- From:
Journal of Medical Postgraduates
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Melanoma inhibitory activity protein(MIA),also referred to as cartilage-derived retinoic acid-sensitive protein(CD-RAP),is expressed not only in malignant melanoma,but also in chondrocytes.MIA/CD-RAP act as a biological marker for the evaluation of the status of cartilage in the study of cartilage destruction.This article reviews the biochemistry,construction,physiological function of MIA/CD-RAP in cartilage destruction and the research progress in these aspects.
