Progress of The Research on Retinoic Acid Inducible Gene I
- VernacularTitle:维甲酸诱导基因Ⅰ研究进展
- Author:
Yingyu CUI
- Publication Type:Journal Article
- Keywords:
retinoic acid inducible gene-Ⅰ(RIG-Ⅰ), RNA helicase, inducible expression, innate immunity, autoregulation
- From:
Progress in Biochemistry and Biophysics
2006;0(04):-
- CountryChina
- Language:Chinese
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Abstract:
RIG-Ⅰ, the abbreviation of retinoic acid inducible gene-Ⅰ, can be induced to express in many type cells by various stimuli. Recently, it was identified as an intracellular regulator for RNA virus-induced antiviral response in innate immunity. Its discovery, expression induction, structure, research status of its function, homologous proteins and functional mechanism etc. were summarized, and its further research pulses are also prospected meanwhile.
