Factors influencing the differentiation of dopaminergic neuron in vivo and in vitro
- VernacularTitle:影响多巴胺能神经元体内外分化的因素
- Author:
Meiling CHEN
;
Yuefei SHEN
- Publication Type:Journal Article
- Keywords:
neural stem cells;
dopaminergic neuron;
differentiation
- From:
Basic & Clinical Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson’s disease is resulted from the progressive degeneration and from the loss of dopaminergic neurons in Substantia Nigra. Current researches focuson the optimum conditions in vivo and in vitro associating the differentiation as well as survival of dopaminergic neurons,in order to get sufficient dopaminergic neurons for cell-replacement therapy in Parkinson’s disease. This paper reviewed influential factors of neural stem cells differentiate into dopaminergic neurons in vivo and in vitro.
