Abscisic acid inhibits proliferation of human hepatocarcinoma cells
- VernacularTitle:脱落酸抑制人肝癌细胞增殖
- Author:
Yonggang LU
;
Jing TAN
;
Jie ZHANG
;
Lanqing MA
;
Feng GUO
;
Yongzhang GUO
- Publication Type:Journal Article
- Keywords:
abscisic acid;
hexamethylenebisacetamide;
SMMC-7721 human-hepatocarcinoma cell;
cell proliferation;
inhibition
- From:
Basic & Clinical Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the mechanism of Depression proliferation in human hepatocarcinoma cells by Abscisic acid.Methods To detect protein expression o of P53,Ki-67 and Cyclin D1 by immunocyte chemistry; detect mRNA expression of P53 and telomerase by RT-PCR. Results The protein expression level of mtP53, Cyclin D1, Ki-67 and the mRNA expression level of mtP53 and hTERT all decreased in cells treated by ABA,HMBA and ABA+ HMBA(P
