Relationship between anti-Hp-IgG seroprevalence and HBV load and HBV genotypes in patients with chronic hepatitis B
- VernacularTitle:慢性乙型肝炎患者血清抗Hp抗体检测及抗Hp抗体与HBV载量和HBV基因型的关系
- Author:
Yonggui ZHANG
;
Jiangbin WANG
;
Shangwei JI
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
hepatitis B,chronic;
HBV DNA
- From:
Journal of Jilin University(Medicine Edition)
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the role of Helicobacter pylori(Hp) on chronic hepatitis B.Methods The seroprevalence of Hp infection and the quantity and genotyping of HBV DNA in 376 patients with chronic hepatitis B,including chronichepatitis group,cirrhosis group and HBV-related hepatocellular carcinoma(HCC) group,were detected,and compared with control and gastritis groups.Results Hp seropositivities in chronic hepatitis B group(56.2%),cirrhosis group(69.9%),HCC group(75.0%) were higher than that in control group(43.4%)(P0.05),the Hp seropositivities in cirrhosis and HCC groups were higher than that in chronic hepatitis group(P0.05).Conclusion Seroprevalence of antibodies to Hp in patients with chronic hepatitis B increases significantly,and Hp seropositivity increases with the pathological changes of chronic hepatitis B.
