Expression of FHIT in oral squamous cell carcinoma and significance
- VernacularTitle:口腔鳞状细胞癌组织脆性组氨酸三聚体蛋白的表达及意义
- Author:
Ying GAO
;
Wenxin GAO
;
Tao YANG
;
Riwen JIANG
- Publication Type:Journal Article
- Keywords:
oral squamous cell carcinoma;
fragile histidine triad;
immunohistochemistry
- From:
Journal of Jilin University(Medicine Edition)
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of fragile histidine triad(FHIT) in oral squamous cell carcinoma(OSCC),and discuss its role and significance in OSCC.Methods Immunohistochemical method was used to detect the expressions of FHIT in 48 cases of OSCC and 26 normal oral mucosa.Results The positive expression rate of FHIT in normal oral mucosa was 76.92%(20/26).Among 48 OSCC patients,the positive rate of FHIT(43.75%) was lower than that in normal oral mucosa(P0.05),but FHIT protein content was significantly associated with differentiation(P
