Advancement of molecular targeted therapies in squamous cell carcinoma of head and neck
10.3760/cma.j.issn.1673-422X.2010.01.013
- VernacularTitle:头颈部鳞癌分子靶向治疗进展
- Author:
Zhengcai LI
- Publication Type:Journal Article
- Keywords:
Head and neck neoplasms;
Carcinoma,squamous cell;
Epidermal growth factor;
Vascular endothelial growth factor
- From:
Journal of International Oncology
2010;37(1):40-42,75
- CountryChina
- Language:Chinese
-
Abstract:
Current reseach of molecular targeted therapies in squamous cell carcinoma of head and neck(SCCHN) is particularly active.As epidermal growth factor receptor(EGFR) signaling pathway and angiogenesis play a key role in the growth of SCCHN,EGFR with its downstream effectors and molecular factors implicated in the angiogenesis process,such as vascular endothelial growth factor and its receptors,represent the main targets of new therapeutic agents now.
