Drug Resistance Analysis and Distributed Features of Nosocomial Infection Pathogens
- VernacularTitle:医院感染病原菌分布及耐药分析
- Author:
Pu GUO
- Publication Type:Journal Article
- Keywords:
Nosocomial infection;
Pathogen;
Drug-resistance;
Analysis
- From:
Chinese Journal of Nosocomiology
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To explore the clinical distributed features and drug-resistant conditions of pathogenic bacteria in nosocomial infection in the last three years for the reference to clinical drug administration. METHODS Retrospective analysis was performed about drug-resistant conditions of pathogenic bacteria in nosocomial infection in the last three years from 2004 to 2006. RESULTS Totally 488 pathogenic strains, including 289 strains of Gram-negative bacteria (59.22%);95 strains of Gram-positive bacteria (19.47%) and 104 strains of fungi (21.31%),were isolated from patients in the last three years, the isolation rate of fungi,Acinetobacter baumannii and Enterobacter cloacae tended to increase year by year. They resisted to commonly used antibiotics at different degree, the rate of multiple-resistance was 80.33%. CONCLUSIONS Most pathogens isolated from patients with nosocomial infection are Gram-negative bacteria, which always display multi-resistant tendency to routine antimicrobial agents. The culture of pathogenic bacteria and rational use of antimicrobial agents should be emphasized to decrease the incidence of nosocomial infection, the factors which easily caused nosocomial infection should be reduced as well.