Sterilization by ~(137)Cs Gamma-ray Irradiation on Cytokine Levels in Manually Manipulated Platelet Concentrates
- VernacularTitle:~(137)Cs ?射线辐照对手工分血小板制品细胞因子灭活的研究
- Author:
Ruqing LI
;
Tianlun JIANG
;
Jian HU
;
Wucun LIN
- Publication Type:Journal Article
- Keywords:
137Cs;
Gamma-ray;
Irradiation;
Platelet concentrates;
Cytokine;
Blood transfusion
- From:
Chinese Journal of Nosocomiology
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the sterilization by gamma radiation on the cytokine levels in manually manipulated platelet concentrates, and its practicability. METHODS Manually manipulated platelet concentrates were irradiated by gamma ray at 25 Gy. Detected the quantity of cytokine levels after irradiation on dd 0, 1, 3, and 5. Platelet counts and pH value were detected on the d0 and d5. RESULTS The contents of cytokines increased with storage time both in irradiation and control groups. But the contents of cytokines in the control group increased more significantly than in the irradiation one (P
