Dendritic Cells and Th2 Response Induced by Schistosome Infection
- VernacularTitle:树突状细胞与血吸虫感染的Th2应答
- Author:
Wei ZANG
;
Yujuan SHEN
;
Jianping CAO
- Publication Type:Journal Article
- Keywords:
Dendritic cells;
Th2 response;
Schistosome
- From:
Chinese Journal of Parasitology and Parasitic Diseases
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Dendritic cells act as the major antigen presenting cells in the body and play a central role in intri-guing the adaptive immune response. Protective immunity against schistosome and immuno-pathological response in host caused by eggs are both closely associated with Th2 response. Further understanding on immune mechanism will contribute to the development of vaccines against schistosome infection, as well as the relief of the pathological lesion in schistosomiasis. This article discusses the central role of dendritic cells in the mechanism of Th2 response induced by schistosome (including eggs).