Studies on chemical constituents from the sea cucumber Holothuria impatiens
- VernacularTitle:丑海参的化学成分研究(Ⅰ)
- Author:
Peng SUN
;
Yanghua YI
;
Ling LI
;
Haifeng TANG
- Publication Type:Journal Article
- Keywords:
sea cucumber;
Holothuria impatiens;
triterpene glycoside;
cytotoxicity
- From:
Chinese Journal of Marine Drugs
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the chemical constituents of the sea cucumber Holothuria impatiens collected from the South China Sea.Methods The pure compounds were isolated by extraction,partition and multi-chromatography.Their structures were elucidated on the basis of spectral analysis and chemical evidence.Results Three triterpene glycosides were isolated and identified as holothurin A1(Ⅰ),holothurin A(Ⅱ) and pervicoside C(Ⅲ),together with a physiological substance of adenosine(Ⅳ).Conclusion All were isolated from Holothuria impatiens for the first time.Three glycosides showed significant cytotoxic activities.
