Investigation of VP_7 From Rotaviruse Strains in Ningbo City,China
- VernacularTitle:宁波市一起新生儿轮状病毒腹泻爆发的调查
- Author:
Yan FU
;
Hong GAO
;
Jianyi LIU
- Publication Type:Journal Article
- Keywords:
Rotavirus;
VP7;
Sequence analysis
- From:
Chinese Journal of Vaccines and Immunization
2008;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To know the currently prevalent genotype of rotavirus strains in Ningbo City,which will help to the study of vaccine of group A rotavirus.Methods The VP7 fragments were amplified by RT-PCR and sequence analysis was conducted from 2 of the 11 virus strains.Results VP7 amino acid sequences homogeneity of the two strains Ningbo 06-1 and Ningbo 06-3 was 90.2%.They all shared higher amino acid sequences homogeneity with G1 strain Wa(95.1% and 87.7%,respectively)than with other serotypes(G types)rotavirus(
