Characteristic features of clinical manifestation, imaging and pathology of hypertrophic cranial pachymeningitis (report of 1 case)
- VernacularTitle:肥厚性硬脑膜炎的临床、影像学及病理学特征(附1例报告)
- Author:
Bing CHEN
;
Xiaosu YANG
;
Lifang ZHANG
- Publication Type:Journal Article
- Keywords:
hypertrophic cranial pachymeningitis;
clinic;
imaging;
pathology
- From:
Journal of Clinical Neurology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the characteristic features of clinical manifestation, imaging and pathology in the patients with hypertrophic cranial pachymeningitis (HCP). Methods All clinical data of 1 patient with HCP were studied retrospectively. Results The patient presented with heavy headache, progressive visual acuity decreased and hoarse voice. Brain MRI displayed abnormal strengthening signals in cerebral dura mater, especially in cerebral falx and tentorium of cerebellum. Pathological examination demonstrated chronic inflammation changes including numerous plasmocytes infiltration, accrementition and glassy degeneration of fibrous tissue, formation of granulation tissue. Therapy with corticosteroid hormone showed good effect for this patient.Conclusions HCP mainly presents with headache and paralysis of multiple cranial nerves. Distinctive sign on brain MRI is strengthening signal in cerebral dura. Chronic inflammation is the pathological change of this disease and pathological examination plays important role in diagnosis of HCP.
