Clinical study of Paroxetine combined with psychotherapy in treating post-stroke emotion disorder
- VernacularTitle:脑卒中后情感障碍的心理干预及帕罗西汀治疗的临床研究
- Author:
Jianwei LOU
;
Linping LIANG
;
Yan HE
- Publication Type:Journal Article
- Keywords:
post-stroke,depression,anxiety;
Paroxetine;
psychotherapy
- From:
Journal of Clinical Neurology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the incidence of the post-stroke emotion disorder, the relationship between post-stroke emotion disorder and the location of stroke, and the effects of Paroxetine combined with psychotherapy in treating post-stroke emotion disorder. Methods 181 patients with acute brain stroke were assessed by SDS and SAS. Of these patients, 54 patients met the criteria of depression and anxiety after acute brain stroke. These 54 patients were divided into 2 groups randomly. They were treated with routine anti-stroke medication, routine anti-stroke medication with Paroxetine combined with psychotherapy for 6 weeks, respectively. The rating scales such as SSS, HAMD, HAMA, TESS and so on were used to evaluate the improvement of symptoms and side effects. Results According to the evaluation of SDS or SAS, there were 81 patients (44.75%) with post-stroke emotion disorder. The rate of post-stroke depression with anxiety was 66.67%. Post-stroke depression with anxiety was related to the location of brain stroke, such as frontal cortex,left cerebral hemisphere and basal ganglia (P
