The variabilities of insulin resistance and pancreatic ?-cell hypofunction among cases with different glucose tolerances
- VernacularTitle:不同糖耐量人群胰岛素抵抗和胰岛?细胞功能减退的差异
- Author:
Junqing ZHANG
;
Bin DONG
;
Xiaohui GUO
- Publication Type:Journal Article
- Keywords:
Insulin resistance;
Hypofunction,pancreatic ?-cell;
Oral glucose tolerance test
- From:
Chinese Journal of Diabetes
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To clarify insulin resistances and pancreatic ?-cell hypofunctions in cases with different glucose tolerance. Methods 5523 Chinese underwent OGTT and were classified into normal glucose tolerance (NGT), isolated impaired fasting glucose (IFG), isolated impaired glucose tolerance (IGT), IFG with IGT (IFG+IGT) and type 2 diabetes mellitus (T2DM) groups based on OGTT results. HOMA-IR, HOMA-?△I30/△G30and AUCI of different groups were statistically analyzed by SPSS12.0. Results Compared to NGT group, HOMA-IR was increased by 41%, 19%, 47% and 69% respectively in IFG, IGT, IFG+IGT and T2DM groups (all P
