ESBLs′ Genotypes of Escherichia coli and Klebsiella pneumoniae
- VernacularTitle:大肠埃希菌与肺炎克雷伯菌超广谱?-内酰胺酶基因型研究
- Author:
Huihong CHEN
;
Lizhong HAN
;
Sufei YU
;
Bo SHEN
;
Yiman WANG
;
Jun ZHOU
- Publication Type:Journal Article
- Keywords:
Escherichia coli;
Klebsiella pneumoniae;
ESBLs;
Genotype
- From:
Chinese Journal of Nosocomiology
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the ESBLs ′ genotypes and the resistance of Escherichia coli and Klebsiella pneumoniae in Taizhou Hospital of Zhejiang Province.METHODS We collected 30 strains of E.coli and K.pneumoniae expressing ESBLs,then analyzed their encoding genotypes of TEM,SHV,PER,VEB and CTX genes by PCR and DNA sequencing technology separately.RESULTS There were 26 strains expressing blaCTS-M gene among 30 strains,in which 16 strains belonged to blaCTS-M-9 subgroup genotype,8 strains to blaCTX-M-1,7 strains to blaCTX-M-2,4 strains to blaCTX-M-1 as well as blaCTX-M-2,1 strain to blaCTX-M-2 as well as blaCTX-M-9 and 1 strain belonged to blaCTX-M-1 as well as blaCTX-M-9.CONCLUSIONS The prevalent clinical genotype of E.coli and K.pneumoniae is blaCTX-M-9.
