The Synchronous Detection and Significance of β-Glucuronidase Both in Serum and Tumorous Tissue in Non-Hodgkin Malignant Lymphoma Patient
- VernacularTitle:非何杰金恶性淋巴瘤病人血清及瘤组织中β-葡萄糖醛酸酶同步测定及意义
- Author:
Hong ZHANG
;
Rui ZHENG
;
Bo YANG
;
Jing HU
;
Bin XU
;
Shutao HE
;
Anmin YU
;
Yingjie LIU
- Publication Type:Journal Article
- From:
Journal of China Medical University
2001;30(1):4-5,30
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Our purpose was to explore the change regularity of β-glucuronidase (β-G) in body of patients with Non-Hodgkin malignant lymphoma. Methods: β-G was examined synchronously both in the serum and in the tumor tissue of 13 cases patient with Non-Hodgkin malignant lymphoma by using the method of enzymlinked immunsorbent assay (ELISA) and immunohistochemistry separately. Among them, 3 cases were studied by using the immuno electron microscopic technique. Results: β-G was highly expressed both in the serum and tumorous tissue in patients with non-Hodgkin malignant lymphoma and there was obviously difference as compared with the control group (P<0.01). Conclusion: The combined detection with functional and morphological methods to β-G, it may be assistant target to early discovery and early diagnosis of Non-Hodskin malignant lymphoma.
