Nursing skills for patients receiving sequential living kidney from the relatives and nonmyeloablative syngeneic hematopoietic stem cell transplantation:One case report
- VernacularTitle:亲属活体肾移植过程中非清髓同源造血干细胞序列移植术的护理技术:1例报告
- Author:
Shuping GUAN
;
Xiaofeng TU
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
A male patient aged 23 years with chronic renal failure,who were treated with sequential living related donor kidney transplantation/nonmyeloablative syngeneic hematopoietic stem cell transplantation,were selected in April 2000 at the 153 Central Hospital of Chinese PLA.Donor is his mother.Nonmyeloablative syngeneic hematopoietic stem cells were transplanted after kidney transplantation.Microchimera in the recipient,rejection,infection and graft-versus-host reaction and dosage of immunodepressant were detected,and then compared with the control.Different nursing care plans were performed following different therapies.HLA-DR site,the same as the donor,could be detected in the recipient after 3 months,and present after 3 years.Immunodepressant dosage was half of that in subjects who did not receive hematopoietic stem cell transplantation.No rejection occurred during the 7 years follow-up.Microchimera or immunotolerance can be detected in the recipient following sequential living related donor kidney transplantation/nonmyeloablative syngeneic hematopoietic stem cell transplantation.
