Effects of ShaJi on oxygen metabolism in myocardium of anesthetized thoraco-opened dogs
- VernacularTitle:沙棘对麻醉开胸犬心肌氧代谢的影响
- Author:
Yizhong JIANG
;
Wenwei LU
;
Qi YAO
;
Xia CHEN
- Publication Type:Journal Article
- Keywords:
ShaJi;
coronary blood flow;
oxygen metabolism;
dogs
- From:
Journal of Jilin University(Medicine Edition)
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of ShaJi on the indexes of oxygen metabolism such as coronary blood flow in myocardium of anesthetized thoraco-opened dogs. Methods Dogs were randomly divided into control group,4 and 16 mg?kg-1 ShaJi groups,and positive control group(n=6).The anesthetized thoraco-opened dog models were set up.The administration of intravenous injection was used by femoral vein.The blood pressure,heart rate and coronary blood flow(CBF) were measured.Coronary resistance,myocardial oxygen uptake rate,myocardial oxygen consumption index and myocardial oxygen consumption were calculated.Results Compared with control group,the CBF was increased (P0.05).Conclusion ShaJi can significantly ameliorate oxygen metabolism in myocardium of anesthetized thoraco-opened dogs.
