Anti-proliferation effect of Ginseng Rh_2 on MFC cells
- VernacularTitle:人参皂苷单体Rh_2对小鼠前胃癌MFC细胞的增殖抑制作用
- Author:
Ge WU
;
Shijie YANG
- Publication Type:Journal Article
- Keywords:
Ginseng Rh2;
MFC cells;
cell cycle
- From:
Journal of Jilin University(Medicine Edition)
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the anti-proliferation effect of Ginseng Rh2(G-Rh2)on mouse MFC gastric cells and its mechanism.Methods MFC cells (1.0?109?L-1) were divided into four gourps:control group and G-Rh2(3,10,30 mg?L-1) groups.The cell viability was determined by MTT;the cell cycle was detected by flow cytometry;the protein expression of cyclin D1 and p27kip1 were observed respectively by qualitative and quantitative analysis.Results Compared with control group,the cell viabilities decreased gradually with the increasing of dose and time in G-Rh2(3,10,30 mg?L-1) groups at different time(1,2,4 h)(P
