A Case of Zosteriform Kaposi's Sarcoma after Prednisolon Treatment.
- Author:
Chul Hann KIM
1
;
Dae Hyun KIM
;
Jin Seok JEON
;
Sang Gue KANG
;
Dong Wook KIM
;
Moon Kyun CHO
Author Information
1. Department of Dermatology, Soonchunhyang University Hospital, Seoul, Korea. Mkcho2001@hanmail.net
- Publication Type:Case Report
- Keywords:
Human herpes virus 8;
Iatrogenic immunosuppressive drug-associated Kaposi's sarcoma;
Kaposi's sarcoma;
Zosteriform Kaposi's sarcoma
- MeSH:
Biopsy;
Female;
Glomerulonephritis;
Humans;
Kidney;
Leg;
Middle Aged;
Polymerase Chain Reaction;
Sarcoma, Kaposi;
Skin;
Transplants;
Viruses
- From:Korean Journal of Dermatology
2009;47(5):583-587
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kaposi's sarcoma is a rare lympho-angioproliferative neoplasm with four types of variants: classic, iatrogenic immunosuppressive drug-associated, AIDS-related and Africa-endemic Kaposi's sarcoma. Most immunosuppressive drug- associated Kaposi's sarcomas usually occur after a kidney transplant or after receiving immunosuppressive therapy. A 64-year-old female patient showed numerous purpuric nodules and smaller erythematous plaques on the right lower leg for three months. Previously, the patient was treated with an immunosuppressive drug for rapidly progressive glomerulonephritis for a five-week period. A skin biopsy was performed under the clinical diagnosis of Kaposi's sarcoma. We performed immunohistochemical staining and polymerase chain reaction to detect human herpes virus 8 (HHV-8). We report a case of iatrogenic immunosuppressive drug-associated zosteriform Kaposi's sarcoma that rapidly occurred five weeks after prednisolon therapy in a rapidly progressive glomerulonephritis patient.
