Effect of low dose radiation on biological characteristics of human mesenchymal stem cells from bone marrow
- VernacularTitle:低剂量辐射对人骨髓间充质干细胞生物学特性的影响
- Author:
Yan YANG
;
Xiao CHEN
;
Wei LI
;
Guanjun WANG
- Publication Type:Journal Article
- Keywords:
bone marrow mesenchymal stem cells;
low dose radiation;
cell cycle;
apoptosis.
- From:
Journal of Jilin University(Medicine Edition)
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of low dose radiation(LDR) on biological characteristics of human mesenchymal stem cells from bone marrow (BM-MSC). Methods The P4,P5,BM-MSC were exposed to X rays at the dose of 50,75,and 100 mGy (dose rate 12.5 mGy?min-1). The cell growth,cell cycle and apoptosis of BM-MSC treated with LDR were determined. Results Compared iwth control group,the cell growth rates of BM-MSC treated with LDR(50,75,100 mGy) were obviously increased from the fifth day(P
