A Case of Milker's Nodule.
- Author:
Kyoung Eun JUNG
1
;
Sun Nam KOONG
;
Ji Min CHUNG
;
Jong Wook PARK
;
Myung Hwa KIM
;
Yong Woo CINN
;
Ki Woong RO
Author Information
1. Department of Dermatology, College of Medicine, Dankook University, Cheonan, Korea. ivymyung@hanmail.net
- Publication Type:Case Report
- Keywords:
Milker's nodule;
Pseudocowpox virus
- MeSH:
Animals;
Cattle;
Epidermis;
Female;
Hand;
Humans;
Inclusion Bodies;
Microscopy, Electron;
Parapoxvirus;
Polymerase Chain Reaction;
Pseudocowpox virus;
Skin;
Virion
- From:Korean Journal of Dermatology
2009;47(5):625-628
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Milker's nodule is a harmless skin lesion that's caused by the paravaccinia virus (also called pseudocowpox virus), which is a member of the genus Parapoxviridae. It occurs worldwide, but it is prevalent only in individuals who are in close contact with cattle. We report here on a woman who presented with a dusky purpuric center surrounded by a white or gray ring and an outer red halo on the back of the right hand. Histologically, intracytoplasmic inclusion bodies were evident in the upper epidermis, and these revealed cylindrical virus particles on electron microscopy. Parapoxvirus was identified by polymerase chain reaction with using pan-parapoxvirus primer 1 (PPP-1) and PPP-4.
