Relationship between IL-17 and autoimmune diseases
- VernacularTitle:IL-17与自身免疫性疾病关系的研究进展
- Author:
Bixia TANG
;
Xuan ZHANG
;
Fulin TANG
- Publication Type:Journal Article
- Keywords:
IL-17,Th17,autoimmune diseases
- From:
Basic & Clinical Medicine
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
IL-17 is the cytokine secreted by the subgroup of CD4+T cells named Th17.The differentiation,proliferation and cytokine secretion of Th17 are regulated by TGF-?,IL-6,IL-15 and IL-23.IL-17 modulates the production and secretion of proinflammative factors,CXCs,affecting the transfer of neutrophil,the activation and the absorption of bone.It suggests that IL-17 also plays an important role in the pathogenesis of autoimmune diseases.
