In vitro and in vivo anti-tumor effects of dendritic cell vaccines sensitized by NCI-H460 lung cancer cell line
- VernacularTitle:肺癌细胞致敏树突状细胞疫苗的体内外抗肿瘤作用
- Author:
Yongqiang FU
;
Zaiyun ZHANG
;
Yuean LIU
;
Xusheng LI
- Publication Type:Journal Article
- Keywords:
dendritic cells;
vaccine;
lung neoplasms;
cell fusion;
interleukin-18
- From:
Chinese Journal of Cancer Biotherapy
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
DC group.IL-12 secretion in IL-18/fusion group was higher than that in the fusion group,and IL-12 in the pulsed DC group was higher than that in the DC group.The in vitro killing rates of the 4 groups were 79.73%,50.68%,35.81% and 4.05%,respectively.Tumor forming time in IL-18/fusion group([12.82?2.85]d) was longer than those in the pulsed DC group([8.52?1.97]d,P
