Efficacy and Safety of Combination Therapy with Amlodipine Plus Terazosin in Patients with Essential Hypertension
- VernacularTitle:氨氯地平联合特拉唑嗪治疗原发性高血压的短期疗效和安全性
- Author:
Chen MAO
;
Guangyun MAO
;
Shanqun JIANG
;
Yu WANG
;
Xiping XU
- Publication Type:Journal Article
- Keywords:
Eessential hypertension;
Amlodipine;
Terazosin
- From:
Chinese Journal of Hypertension
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the short-term efficacy and safety of combination therapy with amlodipine and terazosin in middle aged and old male patients with essential hypertension.Methods Randomized,prospective,parallel study was carried out in middle aged and old male patients with essential hypertension in Anqing community between August 2005 and February 2006.Antihypertensive efficacy and safety of the combination therapy were evaluated in 508 patient who completed the study.Results After 4 weeks treatment,the average reduction of SBP were 4.0?15.0,17.5?15.8 and 20.0?15.9 mm Hg in Terazosin group,amlodipine group and combination group,respectively(P