Efficacy observation of Shenmai injection in treating neonatal hypoxic-ischemic encephalopathy
- VernacularTitle:参麦注射液治疗新生儿缺氧缺血性脑病的疗效观察
- Author:
Jun WANG
;
Hongxia JIANG
;
Changmei ZHOU
- Publication Type:Journal Article
- Keywords:
hypoxic ischemic encephalopathy;
Shenmai injection;
S-100?;
NSE;
neonate
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the therapeutic effect of Shenmai injection(SMI)on neonatal hypoxic-ischemic encephalopathy(HIE)and it's possible mechanism.Methods 45 neonates with HIE were randomly divided into the SMI treatment group and routine treatment group.At the basic of routine treatment,the SMI treatment group was treated with 10 ml SMI added into 10% GS 30~50 ml via injecting into veins once a day for 7~10 d.The levels of serum S-100?,NSE were measured at 1 d,3 d,6 d after treatment.The development quotients(DQ)was evaluated at 3-month-old infants.Results Compared with routine treatment group,symptoms of nervous system in SMI treatment group were recovered obviously faster,the hospitalization time was shorter(all P
