Effects of mild hypothermia on secondary cerebral vasospasm and levels of endothelin,calcitonin gene-related peptide in CSF and plasma in patients with subarachnoid hemorrhage
- VernacularTitle:亚低温治疗对蛛网膜下腔出血继发性血管痉挛及脑脊液和血浆内皮素、降钙素基因相关肽的影响
- Author:
Hongxia XING
;
Yumei WANG
;
Hehua LI
- Publication Type:Journal Article
- Keywords:
mild hypothermia;
subarachnoid hemorrhage;
cerebral vasospasm;
endothelin;
calcitonin gene-related peptide
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of mild hypothermia on secondary cerebral vasospasm and levels of endothelin(ET),calcitonin gene-related peptide(CGRP)in CSF and plasma in patients with subarachnoid hemorrhage(SAH).Methods 56 patients with SAH were randomly divided into mild hypothermia group and control group.Based on the routine treating method,patients of mild hypothermia group were treated with local mild hypothermia.The levels of ET,CGRP in CSF and plasma were detected before and after treatment.And the incidence rates of secondary cerebral vasospasm cases were compared between the two groups.Results(1)At 7 d,14 d after treatment,ET levels in CSF and plasma in mild hypothermia group were significant lower than those in control group(P
