Advances in researches on bone morphogenetic protein-2 for bone repair
- VernacularTitle:骨形态发生蛋白-2促进骨缺损修复的研究进展
- Author:
Pengju YUE
;
Jianning ZHAO
- Publication Type:Journal Article
- Keywords:
Bone morphogenetic protein;
Repair;
Cytokine
- From:
Journal of Medical Postgraduates
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
The bone morphogenetic protein(BMP),as a member of the transforming growth factor beta(TGF-?) family,plays a pivotal role in the formation,induction,maintenance and repair of the bone.The expression level of BMPs has a direct influence on the differentiation of mesenchymal osteoprogenitors and the regulation of osteoblastic features.Among BMPs,BMP-2 is the most widely studied and has the strongest activity in inducing bone formation.This article reviews the current advances in researches on BMP-2 for bone repair.