Morphology changes and the expression of phosphatidylserine in stored platelets
- VernacularTitle:贮存血小板形态变化与凋亡因子磷脂酰丝氨酸表达的研究
- Author:
Wen XIONG
;
Zhankun ZHU
;
Xuqun WU
- Publication Type:Journal Article
- Keywords:
Apheresis;
Platelets morphology;
Storage;
Phosphatidyl serine(PS);
Flow cytometry(FCM)
- From:
Chinese Journal of Blood Transfusion
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the morphology changes and the expression of phosphatidyl serine(PS) in apheresis platelets(Plts) during storage,also to analyze their relationship,in order to provide laboratorial evidence for the in vitro storage period of plts.Methods The morphological changes of plts during 8-day storage were detected by May-Grunwald-Giemsa dyeing method,and the expression of PS on platelet membrane was tested by flow cytometry(FCM).Results The morphological lesions appeared on the fourth day of storage,because the modified morphological score(MMS) of 4-day group was significantly lower than that of fresh plts(t=2.341,P
