Strategies Exploited by Viruses for Evading The RNAi
- VernacularTitle:病毒逃避RNAi的策略
- Author:
Yushu ZHENG
;
Pu ZHAO
;
Xingyou LIU
- Publication Type:Journal Article
- Keywords:
RNAi, virus, evading, strategies
- From:
Progress in Biochemistry and Biophysics
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
RNAi is an efficient antiviral system, and viral gene-specific siRNAs are very promising antiviral inhibitors. However, many viruses have evolved highly sophisticated mechanisms that interfere with both siRNA- and miRNA-guided silencing pathways. Deeper understanding the strategies exploited by viruses provides the basis for the development of effective RNAi-based therapies that prevent viral evading. Therefore, the latest progress on the strategies exploited by viruses for evading the RNAi is reviewed.
