Dynamic Changes and Clinical Significance of Serum TNF-? and IL-10 of Nosocomial Infection in Patients with Severe Viral Hepatitis
- VernacularTitle:TNF-?和IL-10在重症肝炎医院感染中的作用及临床意义
- Author:
Ping WEI
;
Linglan ZENG
- Publication Type:Journal Article
- Keywords:
Severe viral hepatitis;
Nosocomial infection;
TNF-?;
IL-10
- From:
Chinese Journal of Nosocomiology
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the dynamic changes and clinical significance of TNF-? and IL-10 of nosocomial infection in patients with severe viral hepatitis.METHODS The study included 40 patients with severe viral hepatitis,their nosocomial infection was treated with antibiotic therapy.Serum levels of TNF-? and IL-10 were measured at baseline and 5 d,10 d and 15 d after the first antimicrobial dose.The patients were divided into 2 groups: infection be controlled group and infection be not controlled group by therapeutic efficacy.RESULTS The serum concentrations of TNF? and IL-10 were elevated in all patients when compared with the healthy control group(P
