Piperacillin/tazobactam for Acute Exacerbation of Chronic Obstructive Pulmonary Disease with Pulmonary Encephalopathy:A Clinical Analysis
- VernacularTitle:哌拉西林/他唑巴坦治疗急性加重期慢性阻塞性肺病并肺性脑病临床分析
- Author:
Zaichun DENG
;
Lei CHEN
;
Yiming YU
;
Li WANG
;
Weihua WANG
- Publication Type:Journal Article
- Keywords:
Piperacillin/tazobactam;
Ceftazidime;
AECOPD;
Pulmonary encephalopathy
- From:
Chinese Journal of Nosocomiology
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the clinical efficacy of piperacillin/tazobactam for acute exacerbation of chronic obstructive pulmonary disease(AECOPD) with pulmonary encephalopathy.METHODS Seventy three cases of AECOPD with pulmonary encephalopathy were randomized into piperacillin/tazobactam group and ceftazidime group,and sputum culture was underwent for each case before and after treatment.RESULTS The total efficacy rates and bacterial clean rates in piperacillin/tazobactam group and ceftazidime group were 91.67% and 88.89%,75.68% and 57.89%,respectively,and the differences between the two groups were statistically significant.CONCLUSIONS It suggested that piperacillin/tazobactam be a more effective drug for AECOPD with pulmonary encephalopathy.
