Action of corn filament beverage on falling blood fat in hyperlipemia rats and mice
- VernacularTitle:玉米花丝饮品对高脂血症鼠的降血脂作用
- Author:
Dawei WANG
;
Xiuying XU
;
Tingting LIU
- Publication Type:Journal Article
- Keywords:
zea mays;
hyperlipidemia;
models,animal
- From:
Journal of Jilin University(Medicine Edition)
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the action of lowering blood fat of corn filament beverage(CFB) on hyperlipemia rats and mice.Methods Sixty rats were randomly divided into control group,alloxan model group,kanglishu capsule 0.70 g?kg-1 group,CFB 7.00,3.50,1.75 mL?kg-1 groups(n=10).Rats in each group were exhibited once a day for 21 d,on the seventh day,fourteenth day,twenty-first day, the contents of serum total cholesterol(TCHO) and triglyceride(TG) were determined,and liver malonaldehyde(MDA) level was measured.Another 60 mice were divided into 6 groups with the method mentioned above,mice in each group were exhibited once a day for 14 d,on the fourteenth day,the serum contents of TCHO and TG were determined,and liver MDA level was determined.Another 72 mice were randomly divided into control group,egg yolk model group,Expellant and Cleanning Fat Capsule 0.4 g?kg1 group,CFB 10.0,5.0,2.5 mL?kg-1 groups(n=12).Mice in each group were exhibited once a day for 10 d.16 h before the last administration,except control group,the mice in other groups were injected with 75% yolk physiological salt solution 0.5mL through the abdominal cavity,and began to starve,1 h after the last administration, the contents of serum TCHO and TG were determined,and liver MDA level was measured.Results Compared with alloxan model group,TCHO and TG in hyperlipemia rats of CFB 7.00 mL?kg-1 all reduced obviously(P