Moxifloxacin in Treatment of Lower Respiratory Tract Infection:Clinical Trials
- VernacularTitle:莫西沙星治疗下呼吸道感染的临床研究
- Author:
Yuguang LI
;
Ailan ZHANG
;
Ronghui WU
;
Lijun MA
- Publication Type:Journal Article
- Keywords:
Moxifloxacin;
Levofloxacin;
Lower respiratory tract infection
- From:
Chinese Journal of Nosocomiology
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the efficacy and safety of moxifloxacin in treating lower respiratory infection.METHODS Totally 102 patients were enrolled in this study,but 3 cases were infixed or weeded.Fifty cases of trial group were given 400mg of moxifloxacin intravenously,once a day for 7-14 days,49 cases of control group were given 400mg of levofloxacin intravenously,once a day for 7-14 days.RESULTS The clinical efficacious rates of moxifloxacin and levofloxacin were 94.0% and 79.6%,respectively.The bacterial clearance rates of moxifloxacin and levofloxacin were 94.3% and 77.8%,respectively.There was significant difference(P0.05) between two groups.CONCLUSIONS Moxifloxacin injection is an effective and safe antibiotics for the treatment of lower respiratory tract infection.
