Clinical significance of diversity of serum LAP during pregnancy
- VernacularTitle:中晚期孕妇血清亮氨酸氨基肽酶水平及其临床意义
- Author:
Kui ZHANG
;
Hongxia WEI
;
Zhiqun WANG
;
Fang QIU
;
Li WANG
;
Guangyu GU
;
Xunyang LUO
- Publication Type:Journal Article
- Keywords:
leucine aminopeptidase;
pregnancy
- From:
Chinese Journal of Clinical Laboratory Science
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explain the physiological properties of serum leucine aminopeptidase (LAP) and discuss the different levels and clinical meaning of serum LAP during the second and the third trimester of gestation.Methods Rate turbidimetry was used to assay serum LAP activity of 175 pregnant women in the second trimester of gestation, among whom 162 were normal and 13 were intrahepatic cholestasis of pregnancy (ICP), and 302 pregnant women in the third trimester of gestation, among whom 215 were normal, 76 were ICP, 6 were pregnancy-induced hypertension syndrome and 5 were premature delivery, and 100 healthy or non-pregnant women.Results Serum LAP activity of pregnant women in the group of the second trimester of gestation was (140.43?64.39) U/L, in the group of the third trimester of the gestation was (234.72?93.53) U/L, and in control group was (72.62?15.31) U/L. The serum LAP activities of the two pregnant groups were much higher than that of control group (P
