Study on expression of CD174, cyclin D1 and cyclin E in gastrointestinal tumors
- VernacularTitle:CD174、细胞周期素D1、E在消化道肿瘤中的表达
- Author:
Yuping FAN
;
Guohua TAO
;
Xingjian CAO
;
Yaming WANG
;
Xianjuan ZHANG
- Publication Type:Journal Article
- Keywords:
CD174;
cyclin D1;
cyclin E;
Gastrointestinal tumors
- From:
Chinese Journal of Clinical Laboratory Science
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the expression levels of CD174, cyclin D1 and cyclin E in gastrointestinal tumor tissues, analyze the correlation among CD174, cyclin D1 and cyclin E, and evaluate the expression level of CD174 for diagnosis and prognosis of gastrointestinal tumors.Methods Flow cytometry was used to determine the expression of CD174, cyclin D1 and cyclin E on surface of the cells which were collected from the tumor tissues and distant part beside the same tumor and suspended. The expression and topography of CD174 in gastrointestinal tissue were investigated with immunohistochemical staining.Results The expression of CD174 in tumor tissues was obviously lower than that in distal noncancerous tissues (P
