Changes of plasma ANP and BNP in plasma before and after percutanous balloon mitral valvuloplasty
- VernacularTitle:经皮球囊二尖瓣成形术前后心房利钠肽和脑钠肽的变化
- Author:
Huihui BAO
;
Xiaoshu CHENG
;
Renqian YANG
- Publication Type:Journal Article
- Keywords:
Mitral valve stenosis;
Heart catheteriration;
Atrial natriuretic factor;
Natriuretic peptide, brain;
Hemodynamics phenomena
- From:
Chinese Journal of Interventional Cardiology
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in plasma and the correlation of ANP and BNP with hemodynamic parameters in patients with sinus rhythm or atrial fibrillation after percutanous balloon mitral valvuloplasty (PBMV). Methods Thirty-six patients with rheumatic mitral stenosis undergoing first time successful PBMV were enrolled in the study. Among a total of 36 patients, 11 were in sinus rhythm (SR group) and 25 had atrial fibrillation (Af group). The levels of ANP and BNP were assayed before and at 1 day and 3 days after the procedure. Hemodynamic parameters were measured by echocardiography and left atrial pressure (LAP) and pulmonary artery pressure (PAP) were assessed instantly by cardiac catheter before and after PBMV. Results After PBMV,the ANP levels gradually decreased (216.09?73.84 pg/mL; 188.70?59.22 pg/mL; 140.70?41.53 pg/mL, respectively, before, at one day and three days after procedure, P