Evaluation of coronary collateral circulation with intracoronary Doppler ultrasound after acute occlusion in pigs
- VernacularTitle:冠状动脉内多普勒超声评价猪急性冠状动脉闭塞侧支循环状态及影响因素
- Author:
Wu XU
;
Chaoqun ZHANG
;
Jiandong WU
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Echocardiography;
Doppler,color;
Collateral circulation;
Swine,miniature
- From:
Chinese Journal of Interventional Cardiology
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the formation of coronary collateral circulation with intracoronary Doppler ultrasound in pigs after acute occlusion and the influence of nitroglycerin and phentolamine on it.Methods The blood flow spectrun was detected in 14 pigs using intracoronary Doppler ultrasound before and after acute occlusion of the left circumflex artery (LCX) and its response to nitroglycerin and phentolamine.The average peak velocity (APV) and the diastolic systolic velocity ratio (DSVR) were recorded. Results The APV of the LCX decreased significantly at 10 min after acute occlusion (0.97?1.05 vs 25.78?4.36 cm/s,P0.05). Conclusion Intracoronary Doppler ultrasound can be used to evaluate coronary collateral circulation. The formation collateral circulation was insufficient after acute occlusion of coronary artery in pigs and nitroglycerin or phentolamine can improve the blood flow.