Expression of intercellular adhesion molecule-1 and E-selectin in different stages of chronic obstructive pulmonary disease
- VernacularTitle:慢性阻塞性肺疾病不同时期细胞间黏附分子-1和E-选择素的表达及意义
- Author:
Xigang MA
;
Xiangyuan CAO
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Intercellular adhension molecule-1;
E-selectin
- From:
Journal of Medical Postgraduates
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the relationship of intercellular adhesion molecule-1(ICAM-1) and E-selectin with the pathogenesis of chronic obstructive pulmonary disease(COPD). Methods: The serum soluble ICAM-1(sICAM-1) and E-selectin(sE-selectin) and tumor necrosis factor-?(TNF-?) from 45 exacerbated COPD patients,35 stable patients and 30 healthy as controls were measured by double antibody sandwich quantitative enzyme linked immunosoebent assay(ELISA). Results: The levels of both sICAM-1 and sE-selectin in the exacerbated group were significantly higher than those in the control(P
