Significance of(1,3)-?-D-Glucan Detection in Three Kinds of Fluid Samples from Rat Model of Systemic Trichosporosis
- VernacularTitle:大鼠系统性毛孢子菌病模型3种体液标本(1,3)-?-D-葡聚糖检测
- Author:
He ZHU
;
Rongya YANG
;
Wenling WANG
;
Xin FAN
;
Xun ZHAO
;
Congmin WANG
- Publication Type:Journal Article
- Keywords:
Systemic trichosporosis;
(1,3)-?-D-glucan;
Rat
- From:
Chinese Journal of Nosocomiology
2004;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To observe the significance of(1,3)-?-D-glucan in different humor samples on the rat model of systemic trichosporosis.METHODS Established the animal model with systemic infection of trichosporosis,to collect the bronchoalveolar lavage fluid(BALF),plasma and urine samples for determining,and checked with G-test,nested PCR and fungus culture.RESULTS In the earlier infection(10d),the sensitivity of G-test in the samples of plasma,BALF and urine were 80.00%,86.67%,and 6.67%,respectively,and had significant difference with control group.In the 30 plasma samples,the average sensitivity of G-test and nested-PCR blood fungus culture was 76.76%,68.85%,and 3.33%,respectively.With the statistical analysis,the sensitivity of G-test had significant deviation than fungus culture(P
