Clinical Therapeutic Effect of Levofloxacin Combined with Cefoperazone-sulbactam on Pulmonary Infection Caused by Multidrug-resistant Bacillus Infection
- VernacularTitle:左氧氟沙星联合头孢哌酮/舒巴坦治疗肺部多药耐药杆菌感染疗效观察
- Author:
Wen LI
;
Bin WU
- Publication Type:Journal Article
- Keywords:
Levofloxacin;
Cefoperazone-sulbactam;
Multidrug-resistant bacillus;
Pulmonary infection;
Therapeutic effect
- From:
Chinese Journal of Nosocomiology
2004;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To observe the clinical therapeutic effect of levofloxacin combined with cefoperazone-sulbactam on pulmonary infection caused by multidrug-resistant(MDR) bacillus infection.METHODS Eighty five patients with pulmonary infection caused by MDR bacillus infection were randomly divided into treatment group and control group,combined levofloxacin and cefoperazone-sulbactam were used in 45 patients of treatment group,ceftriaxone sodium was used in 40 patients of control group,their therapeutic effect was observed 7 days later.RESULTS Thirty four patients of treatment group were cured,7 patients with excellence,3 patients with improvement and only 1 patient was invalid.The total effective rate was 91%.Clinical manifestation such as cough,expectoration,and dyspnea had obviously improved.Sputum culture darkening rate was high.CONCLUSIONS Combined therapy of levofloxacin and cefoperazone-sulbactam has definite therapeutic effect on pulmonary infection caused by MDR bacillus infection.
