Drug Resistance of Staphylococcus aureus: Current Situation and Clinically Therapeutic Countermeasures
- VernacularTitle:金黄色葡萄球菌耐药的现状及临床治疗对策
- Author:
Jinghua JIANG
;
Wenguang CHEN
;
Zebao ZHANG
;
Ying TAO
;
Yachun GUO
;
Zongxin WANG
- Publication Type:Journal Article
- Keywords:
Staphylococcus aureus;
Antibacterials;
Vancomycin;
Drug resistance surveillance;
Treatment
- From:
Chinese Journal of Nosocomiology
2004;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To analyze the current situation of the hospital.and the community-acquired infections due to Staphylococcus aureus(SAU) and provide the reference for clinical reasonable use of drugs.METHODS The clinically isolated S.aureus strains during 2004-2006 were collected,cultured and identified.Their susceptibilily to 16 kinds of antibacterials was detected by K-B or MIC and WHONET5 software was used to analyze the result.RESULTS From 440 S.aureus strains,the meticillin-resisstant S.aureus(MRSA) was 260 accounting for 59.1%;the meticillin-sensitive S.aureus(MSSA) was 180 accounting for 40.9%.The resistant rate of SAU to penicillin G was the highest(85.5%),that to vancomscin was 0.CONCLUSIONS MSSA still keeps fairly good sensibility to most antibacterial medicine,but MRSA shows the multidrug resistance,except to vancomycin.For this studying the resistance mechcnism of Staphylococcus and continuously detecting the emergence of vancomycin-intermediat and vancomycin-resistante S.aureus have a significant clinicil importance.
