Effect of Sonic Hedgehog signaling pathway on the embryonic lung development and lung diseases
10.3760/cma.j.issn.1673-4408.2012.02.028
- VernacularTitle:Sonic Hedgehog信号通路在胎肺发育和肺部疾病中的研究进展
- Author:
Yanan SHAO
- Publication Type:Journal Article
- Keywords:
Sonic Hedgehog signaling pathway;
Embryoniclung development;
Lung disease
- From:
International Journal of Pediatrics
2012;39(2):203-205,211
- CountryChina
- Language:Chinese
-
Abstract:
Sonic Hedgehog (SHH) signaling pathway not only plays key roles in embryonic development,but also functions in postnatal development and maintenance of tissue/organ integrity and function.In recent years,it has been found that the SHH signaling pathway was abnormally activated in some lung diseases,which suggested that the SHH signaling pathway may play a part in the development of some lung diseases.This article reviewed the potential role of SHH signaling pathway on the embryonic lung development and lung diseases.
