Effects of telomerase activity on HeLa cell apoptosis induced by influenza viruses
- VernacularTitle:端粒酶在流感病毒诱导HeLa细胞凋亡中的作用
- Author:
Fang GUI
;
Zhuoran ZHANG
;
Yufeng DUAN
;
Zhihang ZHOU
;
Lanju TENG
;
Zhenming LI
- Publication Type:Journal Article
- Keywords:
influenza virus;
tumer cell;
apoptosis;
telomerase
- From:
Basic & Clinical Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the correlation between telomerase activity and apoptosis in HeLa cells induced by influenza viruses.Methods HeLa cells were observed in the electron microscope after they had been infected by influenza viruses type A1,B and an UV exposed strain respectively.Besides,Annexin V-FITC staining flow cytometry(FCM)and PCR-ELISA were used to detect cell apoptosis and telomerase activity in HeLa cells respectively.Results The maximal rate of apoptotic cells induced by influenza virus type B and A1 were 38.65% and 23.94% respectively(P
